The Generational Health Horizon: Investing In Multigenerational Premiums
Sanskriti Thakur is the Founder and Chairwoman of Tower Capital Group.
Investing in the future is critical to ensuring competitiveness today. As healthcare systems strain under rising global demand, a new investment framework is taking shape: generational health. Investment myopia has challenged progress for the generational perspective, in particular for healthcare.
Generational health is the focus on the biological and environmental cascades that have measurable multigenerational effects. This means generational health can have an effect beyond the third generation—that’s more than 219 years of average human lifespan.
The most important and scalable generational health innovations are at the maturing intersections of biology, biome and technology, and are ripe for action now.
Unlike carbon credits or ESG frameworks, the benefits of measurable biological shifts are concrete, visible and easier to quantify. Growth is being fueled by the expanding life sciences and technology sectors, with many areas experiencing double-digit CAGR—some projected to exceed 30% through 2030.
Generational health companies often have multiple revenue models and economic drivers. This can lead to more contracts, revenue streams and non-dilutive capital options, despite regulatory and global hurdles in broader healthcare markets.
The Generational Facets
Both quantifiable and impactful, generational health investments can be simplified into two facets:
1. Bioresilience
These are the cascades that defend and protect the body from toxicity, disease, aging and other physiological stressors.
For example, dysfunction in mitochondria, the cell’s “powerhouse,” can be passed down and is associated with an increased risk of Alzheimer’s disease.
2. Biome
This is the optimization of the lived environment for better short- and long-term health outcomes.
Protecting the biome is essential in a world where over 350 industrial chemicals can be found in blood and urine, many of which can raise the risk of chronic disease.
Intersectional And Premium Submarkets
Investors should focus on forward-looking submarkets that enhance multigenerational well-being, as these are aligned for strong long-term growth amid rising healthcare needs. The following three submarkets are primed for growth, each connected through the pioneering framework of bioresilience and biome:
1. Longevity Biotechnology
Longevity biotechnology, a high-tech subsegment of biotechnology, enhances bioresilience by extending both health and lifespan. The segment targets the biological drivers of aging using data science, genomics and regenerative medicine.
The longevity biotechnology market is projected to grow from $27.2 billion in 2024 to $46.6 billion by 2033.
The global population aged 60 and older is expected to nearly double by 2050. This age group already accounts for over half of U.S. healthcare expenditures.
Early innovations like senotherapeutics, a novel area of therapeutics targeting “zombie cells,” have shown strong results for longevity in preclinical trials, lengthening lifespan in test mice.
2. Family Health
Family health, undervalued and interconnected, showcases mental health, pediatric health and women’s health.
With a current market size of around $471 billion, the mental health market is expected to grow to $615 billion by 2033. Both pediatric and women’s health are projected to grow significantly by 2030, with the pediatric health market rising from $15.9 billion to $19.4 billion, and women’s health increasing from $49.3 billion to $68.5 billion. Together, family health represents over $530 billion in market size.
The mental health facts are alarming, as people with severe mental disorders have a life expectancy that is 10 to 25 years shorter than average. As awareness around mental health rises, the market will continue to grow at a large scale.
Female health and safety support the biome and bioresilience of current and future generations at the individual and community level. Yet today, 53% of pregnancy-related deaths happen postpartum, with 84% being avoidable. Innovative approaches in microchimerism, the exchange of cells between mother and child, offer new regenerative pathways for future care. Capital deployed here can help develop an underserved and growing market while addressing systemic health inequities.
3. Toxicity And Biome Management
Toxicity and biome management focus on protecting the biome by eliminating and regulating environmental toxins. Innovations can protect against autoimmune disease, where incidence has increased by 19% each year for the last three decades.
Growing companies are developing microbiome-derived therapies that restore and guard against autoimmune disease triggered by toxic environmental exposures. Clinical pipelines are addressing cascading effects of pollutants like trichloroethylene (TCE), which is linked to a 40% higher risk of autoimmune disorders.
The global bioremediation market is projected to grow from $16.3 billion in 2024 to $29.4 billion by 2030.
A $3.5 billion federal investment in Superfund sites is accelerating toxin removal. Phytoremediation, which uses plants to clean air, water and soil, also stands out as a natural and economic solution. Early investments in nature-based remediation could offer both return and ESG alignment.
Increasing The Odds
Many innovators will fail, but where generational intervention is a priority, we must increase the odds. Current models are not tuned for generational success. For example, venture backing does not necessarily equate to strategy and execution. Better models are those that incorporate infrastructure and commercial pathways into the promise of venture and other funding mechanisms.
Understanding that generational health is globally reverberating, yet individualized, means considering a life stage approach. This includes:
• Funding models that support generational health include cross-border partnerships, committed commercial strategies, harvested capital and diverse data platforms
• Private and public sectors uniting for generational action, offering alignment and less resistance, as compared to other categories
• Generational companies commanding a premium for the multiplicity of business and societal outcomes
Now Is The Time To Think Generationally
Chronic disease is rising, childhood health costs are climbing, community-based innovation is lagging and global environmental priorities remain unclear. The time to act is now.
As demand continues to rise for measurable, pragmatic and investable health solutions, generational health provides a pathway for durable growth and multigenerational outcomes. This premium category sits at the intersection of well-known biology and scalable technology, creating opportunities to think generationally and reimagine health investment with strategies that support life at every stage, across every generation.
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